Neuroscientist Erin Schuman to deliver the 21st Fredric S. Fay Memorial Lecture on March 31


Distinguished neuroscientist Erin M. Schuman, PhD, will present the 21st Fredric S. Fay Memorial Lecture on Thursday, March 31 at 3 p.m. at the Albert Sherman Center. A reception will follow at Le Cube.

Erin M. Schuman, PhD

Dr. Schuman, Professor of Synaptic Plasticity and Director of the Max Planck Institute for Brain Research in Frankfurt, Germany, will present “Protein Synthesis in Neuronal Synapses”.

Schuman spearheaded seminal research elucidating the importance of generalized local translation in presynaptic knobs and in postsynaptic dendrites and spines. His work addresses a long-standing question in neuroscience of how newly synthesized proteins are detected so rapidly at synapses after nerve stimulation at several microns of mRNA in somates. Early in her career, she tackled this conundrum by visualizing local protein synthesis in dendrites near synapses to enhance synaptic transmission, a cellular correlate of memory.

The Schuman lab continued to probe how protein synthesis occurs locally at synapses by identifying local translation mechanisms, including ribosomes, ribosomal proteins that regulate ribosomal activity, and over 2,500 different mRNAs. Along the way, the lab has pioneered new nanotechnologies, including expansion microscopy with super-resolution microscopy to visualize local protein synthesis and transcriptome analysis of dynamically regulated mRNA in synaptosomes. .

Schuman has received numerous national and international awards, most recently a Vallée Visiting Professor in 2021, and the ALBA-FKNE Diversity Prize and the Louis-Jeantet Prize in 2020. She is an elected member of the National Academy of Sciences as well than several European universities. scientific academies.

The Fred Fay Lecture was created in remembrance of the late UMass Chan Medical School Professor of Physiology and his scientific contributions, particularly in the field of biomedical imaging. The purpose of the conference is to welcome world-class scientists in physiological research who are also great communicators and role models for the next generation of scientists.

The annual scientific seminar resumes after a two-year hiatus due to COVID-19. Registration is requested.


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